Context: While multidisciplinary team approaches to education and practice have been promoted for decades, literature on collaborative efforts in athletic training and nursing remains sparse. Objective: The goal of this article is to provide an example of an interprofessional teaching collaboration in which a simulation scenario was developed between athletic training and nursing education faculty members and to outline the observed benefits and barriers arising from this approach. Background: Interprofessional education and interdepartmental faculty collaboration are increasingly becoming more established and practiced elements of health professionals' education. Bringing together professionals from diverse but interrelated disciplines in a collaborative teaching activity can enhance students' understanding of the health care system and the technical expertise each professional provides in emergent situations. Description: In many health care education programs simulation has been increasingly used as a teaching tool to provide students with opportunities to practice and learn in an environment that mirrors reality as closely as possible. An example of a simulation scenario developed through an interprofessional teaching collaborative is provided as a foundational design for reproduction. Clinical Advantage(s): Interprofessional teaching collaboration of athletic training and nursing faculty can greatly enhance the content and realism of cardiopulmonary simulation for athletic training students when it involves the combined knowledge and experience of these 2 disciplines. Conclusion(s): Interprofessional teaching collaboration in simulation scenarios can greatly enhance learning insights and clinical relevance for athletic training students.