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Prevention Effects Moderate the Association of 5-HTTLPR and Youth Risk Behavior Initiation: Gene x Environment Hypotheses Tested via a Randomized Prevention Design
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Brody, Gene H.; Beach, Steven R. H.; Philibert, Robert A.; Chen, Yi-Fu; Murry, Velma McBride – Child Development, 2009
A randomized prevention design was used to investigate a moderation effect in the association between a polymorphism in the "SCL6A4"("5HTT") gene at 5-HTTLPR and increases in youths' risk behavior initiation. Participation in the Strong African American Families (SAAF) program was hypothesized to attenuate the link between 5-HTTLPR status and risk…
Descriptors: Prevention, At Risk Persons, Adolescents, Genetics
Cumulative Socioeconomic Status Risk, Allostatic Load, and Adjustment: A Prospective Latent Profile Analysis with Contextual and Genetic Protective Factors
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Brody, Gene H.; Yu, Tianyi; Chen, Yi-Fu; Kogan, Steven M.; Evans, Gary W.; Beach, Steven R. H.; Windle, Michael; Simons, Ronald L.; Gerrard, Meg; Gibbons, Frederick X.; Philibert, Robert A. – Developmental Psychology, 2013
The health disparities literature has identified a common pattern among middle-aged African Americans that includes high rates of chronic disease along with low rates of psychiatric disorders despite exposure to high levels of cumulative socioeconomic status (SES) risk. The current study was designed to test hypotheses about the developmental…
Descriptors: Profiles, Public Health, Adolescents, African Americans