"Literacy Express" is a comprehensive preschool curriculum designed for three- to five-year-old children. It is structured around units on oral language, emergent literacy, basic math, science, general knowledge, and socio-emotional development. It can be used in half- or full-day programs with typically developing children and children with special needs. It provides professional development opportunities for staff, teaching materials, suggested activities, and recommendations for room arrangement, daily schedules, and classroom management. Two studies of "Literacy Express" met the What Works Clearinghouse (WWC) evidence standards. The studies included more than 900 three- to five-year-old children attending preschools in Florida and California. The WWC considers the extent of evidence for "Literacy Express" to be moderate to large for oral language, print knowledge, and phonological processing, and small for cognition and math. No studies that met the WWC evidence standards with or without reservations addressed early reading/writing. "Literacy Express" was found to have positive effects on print knowledge and phonological processing, potentially positive effects on oral language and math, and no discernible effects on cognition. (Contains 8 footnotes.) [The following studies are reviewed in this intervention report: (1) Lonigan, C. J. (2006, July). Impact of preschool literacy curricula: Results of a randomized evaluation in a public prekindergarten program. Paper presented at the 13th annual meeting of the Society for the Scientific Study of Reading, Vancouver, British Columbia, Canada; and (2) Lonigan, C. J., Farver, J. M., Clancy-Menchetti, J., and Phillips, B. M. (2005, June). Promoting the development of preschool children's emergent literacy skills: A randomized evaluation of a literacy-focused curriculum and two professional development models. Paper presented at the 12th annual meeting of theSociety for the Scientific Study of Reading, Toronto, Ontario, Canada.]