This report includes new tables which present trends in estimated annual AIDS incidence from 1996-00, by U.S. region, race/ethnicity, and exposure category. Some of the tables include: persons reported to be living with HIV infection and with AIDS, by state and age group; AIDS cases and annual rates per 100,000 population, by metropolitan area and age group and by state and age group; male and female adult/adolescent AIDS annual rates and HIV infection and AIDS cases; AIDS cases by age group, exposure category, and sex; AIDS cases and HIV infection by sex, age at diagnosis, and race/ethnicity; male and female adult/adolescent AIDS cases and HIV infection cases, by exposure category and race/ethnicity; pediatric AIDS and HIV infection cases by exposure category and race/ethnicity; and deaths in persons with AIDS, by race/ethnicity, age at death, and sex. Overall, the number of estimated AIDS cases diagnosed annually declined substantially from 1996-99, though the rate of decline slowed in 1999-00. AIDS incidence increased among women and persons infected through heterosexual contact. From 1999-00, the number of estimated deaths among persons with AIDS declined 11 percent. From 1999-00, the estimated number of persons living with AIDS increased 7.9 percent. (SM)