Collected in this document are reports of the National Institutes of Health's 1989 accomplishments in research on the problem of infant mortality. Reports are provided by the: (1) National Institute of Child Health and Human Development; (2) National Cancer Institute; (3) National Heart, Lung, and Blood Institute; (4) National Institute of Neurological Disorders and Stroke; (5) National Institute of Allergy and Infectious Diseases; (6) National Institute of Environmental Health Sciences; (7) National Institute of Arthritis and Musculoskeletal and Skin Diseases; (8) Division of Research Resources; and (9) National Center for Nursing Research. It is concluded that even though it is disappointing that the nation did not reach the goal for the reduction of infant mortality set at the beginning of the 1980s, there was significant progress toward the goal. The United States had an all-time low infant mortality rate in 1988, and remarkable progress was made during the 1980s in the ability to save the lives of premature and sick newborns. Research directed at reducing infant mortality has intensified in recent years. This research has led to advances in medicine and patient care, and has yielded powerful new technological tools with which to combat the problem. Application of these advances and use of the new tools will ensure that much progress will be made in the coming decade. (RH)