This guide was developed to help vocational teacher educators and special teacher educators prepare prospective teachers for work with students with disabilities. The manual is based on 13 topics identified by a panel of national experts in vocational special education and vocational teacher education as most important for teacher trainees to know. The topics cover the following areas of the vocational preparation of students with disabilities: (1) basic problems and needs; (2) historical and legislative issues; (3) characteristics of the major disability categories; (4) model programs; (5) national resources for free or low-cost information; (6) materials; (7) objectives; (8) developing/adapting assessment procedures; (9) developing/modifying instructional materials; (10) developing/modifying instructional strategies; (11) monitoring/evaluating vocational preparation; (12) identifying appropriate accommodations; and (13) the school-to-work transition planning process. The guide contains samples of several course outlines that have been infused, introductory lecture notes, 24 handouts, activity sheets with answers and explanations, 40 transparency masters, and 29 references. (KC)