This manual is part of a series of materials designed to reinforce essential concepts in physical science through interactive, language-sensitive, problem-solving exercises emphasizing cooperative learning. The materials are intended for limited-English-proficient (LEP) students in beginning physical science classes. The materials are for teams of two students, the student and the tutor, with a separate workbook for each. Questions appear in the student workbook, prompts and answers in the otherwise identical tutor workbook. This combined document consists of the "Tutor Version" followed by the "Student Version." The volumes on problem-solving in biology address a variety of topics, including scientific method, affixes, measurement, classification, the cell, bacteria, the digestive system, nutrition, the circulatory system, the respiratory system, the skeletal and muscular system, the nervous system, the endocrine system, reproduction, integrated systems, genetics, and ecology. For each topic, the unit offers a brief introduction and a series of exercises. An index to specific terms used in the workbook is included. (MSE)