This guide is written for a combined physics-chemistry course taught over a two-year period. The subject matter contains the major ideas in Chemical Education Materials Study (CHEMS) Chemistry and Physical Science Study Committee (PSSC) Physics. The guide includes discussion of text references, laboratory experiments, films, testing and evaluation and a bibliography. It is suggested that the course be taught for two years with single daily periods, but the possibility of modification to a single year course is discussed. (BC)