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ERIC Number: EJ758989
Record Type: Journal
Publication Date: 2005-Nov
Pages: 7
Abstractor: Author
ISSN: ISSN-1470-8175
Teaching Microbial Physiology Using Glucose Repression Phenomenon in Baker's Yeast as an Example
Raghevendran, Vijayendran; Nielsen, Jens; Olsson, Lisbeth
Biochemistry and Molecular Biology Education, v33 n6 p404-410 Nov 2005
The yeast "Saccharomyces cerevisiae" has been used by human beings since ancient times for its ability to convert sugar to alcohol. Continual exposure to glucose in the natural environment for innumerable generations has probably enabled "S. cerevisiae" to grow in fermentative mode on sugars by switching off the genes responsible for respiration even under aerobic conditions. This phenomenon is referred to as the Crabtree effect. The present review focuses on glucose repression in "S. cerevisiae" from a physiological perspective. Physiological studies presented involve batch and chemostat experiments of the wild type and a mutant that lacks a trait partially responsible for the fermentative behavior. Various undergraduate student exercises have been (and can be) formulated to illustrate the concept of glucose repression.
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Publication Type: Guides - Classroom - Teacher; Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A