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Leggett, Victoria; Jacobs, Patricia; Nation, Kate; Scerif, Gaia; Bishop, Dorothy V. M. – Developmental Medicine & Child Neurology, 2010
Aim: To review systematically the neurodevelopmental characteristics of individuals with sex chromosome trisomies (SCTs). Method: A bibliographic search identified English-language articles on SCTs. The focus was on studies unbiased by clinical referral, with power of at least 0.69 to detect an effect size of 1.0. Results: We identified 35…
Descriptors: Intelligence Quotient, Genetics, Referral, Neonates
Bishop, Dorothy V. M. – Journal of Child Psychology and Psychiatry, 2012
Most people have 23 pairs of chromosomes; one set from the mother and one from the father. However, nondisjunction errors during meiosis can lead to a case of trisomy, where there are three rather than two chromosomes. Although such events are not uncommon, they are usually lethal, and account for a high proportion of spontaneous abortions. There…
Descriptors: Genetics, Autism, Neonates, Intelligence Quotient