In this article, we offer a tribute to the memories of Dr. Beatrice Medicine and Dr. Vine Deloria Jr., two of the most revered and celebrated Indigenous educators. We describe the legacy these scholars leave as one that calls on Indigenous communities to survive by both fighting against ongoing colonization and pursuing individual and communal well-being. We respond to reflections offered by Troy Richardson, Donna Deyhle, and Teresa McCarty in this issue. Medicine's and Deloria's scholarship and leadership remind us about the importance of recognizing the wisdom of elders, of developing research that serves a community purpose, and of working toward the self-education of Indigenous peoples through claiming power and sovereignty.