In an era of rapid societal change, institutions of higher education are grappling with how to ensure that lesbian, gay, bisexual, transgender, and queer (LGBTQ) individuals are safe and supported on campus. Many challenges remain as LGBTQ students, faculty, and staff are subject to continued acts of discrimination and subtle microaggressions on a regular basis, according to national assessments of campus climate. When religion and spirituality are salient on campus or in the lived experiences of LGBTQ people, the complexities of faith as it intersects with sexuality and gender identity become increasingly apparent. In this essay, we portray current issues concerning the campus climate in an effort to imagine how Christian higher education leaders might respond in light of institutional aims to promote the spiritual growth of all members of their campus communities.