This research was conducted in the development of courses for students from multiple nations at two California universities, applying cross-cultural tactics in course content and design. The paper examines the evolution of courses in Global Issues and Global Economics, including the theoretical foundations of socioeconomic development, how those developments evolved from and/or have impacted cultural values, the current-day environment of evolving and revolving economic systems (e.g., the transition from centralized states to more decentralized, free-market systems), the impact of those changes on social interaction, and how these topics may be applied with transcultural resonance to the development of university courses with a particular sensitivity to diverse socioeconomic beliefs and systems worldwide.