This study examined language learning strategy and goal orientation of college-level English Language Learners (ELLs) by using a questionnaire survey. It analyzed the relationship between goal orientation and demographic characteristics and further explored the correlation between learning strategy use and goal orientation. The results of the study show that non-Asian ELLs had a greater performance goal orientation tendency than Asian ELLs. ELLs who had bachelor's degree had a higher level of mastery goal orientation, as well as performance-approach goals than those who had master's and doctoral degree. Female ELLs had a higher level of mastery goal orientation than male ELLs. Mastery goal orientation is positively related to all types of strategy, and it possessed the beneficial role in strategy use. Effective instructional methods for ELLs were provided to promote their adopting of mastery goals.