This mixed methods descriptive study examined the effects of job-embedded professional development (JEPD) in reading on the content knowledge and instructional practice of teachers of English learners (ELs). Four first-grade teachers of ELs at one urban elementary school received JEPD over the course of a year. Results of pre- and posttests of teacher knowledge and classroom observations indicated that teachers' reading content knowledge increased and that they used more evidence-based practices. JEPD shows promise as an approach that accommodates teachers' varying levels of knowledge and experience in preparing them to meet the diverse needs of their students.