It seems that dehydration may impair decision-making performance in athletes. Purpose: This study aimed to investigate the influence of dehydration on passing decision-making performance in soccer players. Method: Participants were 40 male soccer players (M[subscript age] = 22.3 ± 2.3 years) who agreed to participate in the study and were randomly assigned to the following conditions: control (CON), dehydration (DEH), and euhydration (EUH). The players played in 2 games of 90 min in duration (2 45-min halves) followed by 2 15-min halves (overtime) with and without proper hydration. The Game Performance Assessment Instrument (GPAI) was considered for the analysis of passing decision making. Results: The GPAI analysis indicated effective reduction in the decision-making index in the DEH condition compared with the EUH and CON conditions, F(2, 38) = 31.4, p < 0.05, ES = 0.8. Conclusions: In conclusion, dehydration may be considered a mediating factor in the passing decision-making performance of male soccer athletes.