Researchers have shown that college students are at an increased risk of experiencing interpersonal violence (IV). One factor that appears to play a role in shaping their likelihood of IV is sexual orientation. However, little is known about this relationship and how IV risk varies across categories of sexual orientation. Utilizing a sample of approximately 43,000 college students from the American College Health Association's National College Health Assessment II, this study examined the prevalence of IV across five categories of self-identified sexual orientation and examined whether sexual orientation was a predictor of IV. Results indicated that, on average, students who identified as lesbian, gay, bisexual, or questioning were significantly more likely to experience IV than their heterosexual counterparts. Implications for prevention and future research are discussed.