Institutions face pressure from governmental agencies and industry to support collaborative activity on campus. This research examines two forms of collaboration, interdisciplinary teaching and research, to better understand the strategies and influences fostering such work. Using Kezar and Lester's (2009) model of intra-organizational collaboration, this study analyzes institutional documents such as strategic plans, public speeches, and reports of 21 research universities in the United States. The results identify key factors necessary to support interdisciplinary collaboration in higher education. (Contains 2 tables.)