The Cattell-Horn-Carroll (CHC) model is a comprehensive model of the major dimensions of individual differences that underlie performance on cognitive tests. Studies evaluating the generality of the CHC model across test batteries, age, gender, and culture were reviewed and found to be overwhelmingly supportive. However, less research is available to evaluate the CHC model for clinical assessment. The CHC model was shown to provide good to excellent fit in nine high-quality data sets involving popular neuropsychological tests, across a range of clinically relevant populations. Executive function tests were found to be well represented by the CHC constructs, and a discrete executive function factor was found not to be necessary. The CHC model could not be simplified without significant loss of fit. The CHC model was supported as a paradigm for cognitive assessment, across both healthy and clinical populations and across both nonclinical and neuropsychological tests. The results have important implications for theoretical modeling of cognitive abilities, providing further evidence for the value of the CHC model as a basis for a common taxonomy across test batteries and across areas of assessment.