This research aims to analyze the Curriculum planning and benefit between departments of beautification in college and the professional courses by using ISM. To understand the link between different professional courses of beautification in college and find out the connections, Department of Cosmetic Science will be taken as an example. The result will benefit to future developing plans of the courses in Department of Cosmetic Science. The object of this research is all Department of Cosmetic Science in college in Taiwan. All professional courses related with Department of Cosmetic Science were discussed. The content and hierarchy of courses were analyzed and summarized by using ISM. By clarifying the suitability of them as well as promoting Department of Cosmetics Science's future development, all three parties, including the courses, lecturers and students, can achieve the best effect from this research.