This article is an examination and a refusal of education as a site of making-up kinds of people. "Indian," "Aboriginal," "Black," "refugee," "special needs," "citizens," "white," "boy," "girl" are but a few of the kinds of people education continues to make up. The social sciences and the humanities have offered critical contributions towards the making-up of human kinds. Drawing from the specific case of Indigenous making-up in Guatemala, this article zooms in to twentieth-century anthropology, its activities, aspirations, and reverberations in contemporary Guatemalan curriculum and pedagogy. With Ian Hacking's framework for making up people, this article proposes a study of difference and race that charts and interrogates the knowledges, experts, and expert institutions implicated in making up particular kinds of people and the effects that their making produces. Finally, and contrary to the popular folklore that "Indigenous" peoples in their imposed "uncivilized" ontology accepted the invader, this article draws from Indigenous refusal. The making-up of people in education sorts, orders, and exploits. This colonial order must be refused. The article offers conceptual cues for refusal from which specific actions can be initiated in school curricula.