The effectiveness of a postsecondary strategic learning course for improving metacognitive awareness and regulation was evaluated through systematic program assessment. The course emphasized students' awareness of personal learning through the study of learning theory and through practical application of specific learning strategies. Students assessed personal gains through pretest and posttest assessments of both metacognitive awareness and regulation. Pretest-to-posttest gains were statistically significant with large, meaningful effect sizes for program participants, including students with disabilities. Evidence supports the effectiveness of the program and, by extension, the value and importance of learning strategies instruction as a powerful educational intervention for students with disabilities. (Contains 3 figures and 2 tables.)