This paper discusses the role and influences of parental involvement and student's motivation on growth mindset. The participants in this study were from three Catholic middle schools in Ghana: One rural all-girls school (N=268); a suburban school (N=448); and an urban school (N=200). Respondents completed Campbell's Inventory of Parental Influence (IPI S6) questionnaire. Six Parental Involvement and three motivational scales were synthesized using exploratory factor analysis. Path analyses were then conducted to determine the factors with direct or indirect impact on growth mindset. Findings indicate direct link between family influences and mindset in all three socioeconomic settings. Also, motivation and parent's expectation have significant direct impact on children's growth mindset.