This study aim is to investigate the activity which maintain the engagement of students and improve student's learning achievement in the herbal medicine module during a distance learning course that was conducted by the faculty of medicine Universitas Indonesia through Student Centered e-Learning Environment (SCeLE). The data collected from log data of 340 students in SCeLE, which consist of the frequency of students accessing the course including access resources and participate in asynchronous online discussion. Bivariate correlation and linear regression analysis were analyzed. The frequency of access to students to learning materials, forum discussion, and the course is a statistically significant impact on student learning outcomes. The coefficient correlation of frequency of student participation in forum discussion, access learning material, access to course to student's final grade are 0.665, 0.709, and 0.755, respectively. The topic which is frequently accessed by students has a higher average score in the final exam. The frequency of participation in forum discussion has a greater influence on student's final grade than the frequency of student accessing learning materials to the final grade in the implementation of distance learning.