This research aims to understand industry participants' opinions about vocational education under the development of Industry 4.0 manpower and its teaching connotation. The study adopted the expert interview method and invited 10 industry experts to hold 2 meetings. According to the research results, the original teaching contents in the departments of junior colleges have been changed and departments have been recombined, so that the schools can now offer courses related to big data analysis, cloud computing, Internet of Things, etc. to meet the demands of Industry 4.0. Higher vocational education has set about establishing a practical classroom based on the concept of Industry 4.0, in order that schools and industry can establish a close cooperation relationship and share resources with each other. Industry can help schools update their equipment and eliminate the gap between learning and practice by equipping students at technical and vocational universities with the right competitiveness under system integration and industry connection.