The current study aimed to investigate the relationship between psychological well-being, self-efficacy and positive thinking, among Prince Sattam Bin Abdul Aziz University's students in Saudi Arabia. To answer the study questions, three questionnaires were administrated, two were submitted by the researcher (psychological well-being and self-efficacy), positive thinking scale by (Radi & Metib, 2017) to 350 university students with range age of 18 to 36 years old. The study adopted a descriptive design to measure the degree of correlation between variables, Results of the study showed that students have moderate psychological well-being level, and that there was a positive relationship between psychological well-being; self-efficacy and positive thinking, also research results indicated that there was a positive relationship between self-efficacy and positive thinking, but the results showed that (gender, faculty, academic level) had no impact on psychological well-being or positive thinking. The impact was within (academic level) on self-efficacy in benefit of master degree group.