Purpose: The purpose of this paper is to study the determinants of blended learning adoption in universities by focusing on faculty's satisfaction. Design/methodology/approach: The research methodology is based on a case study of one of the most ancient University in Europe. The authors administered a questionnaire to the professors that used blended technologies, and the authors conducted clinical interviews with some of the key people involved in the implementation process. Findings: The paper allows to identify the main factors that impact on faculty's satisfaction. Student-related issues seem to be the most important factors influencing faculty satisfaction, while instructor-related issues and especially institution-related issues definitely seem to be less important. Research limitations/implications: The study is focused just on a single case study. Further researches could explore a wider application of this research approach to several universities and different countries. Originality/value: This study is one of the first that analyzed blended learning adoption in historic universities.