Colleges are engaging students in collaborative design courses on diverse projects. More of the courses could be focusing on cross-disciplinary entrepreneurship projects including computer science and information systems students with other disciplinary students. The authors of this paper describe a course that is focusing on collaborative design and cross-disciplinary entrepreneurship on innovation projects by students as members of self-directed teams. The course is involving the students on crowdfunding projects of product prototyping, from which they are learning a marketable repertoire of skills. The findings of this paper will be beneficial to educators in colleges of computer science and information systems considering enriching pedagogical practices to be contemporary with the demands of industry.