Celiac disease is a genetic autoimmune disease in which gluten, a protein found in wheat, rye, barley, and contaminated oats, attacks the lining of the small intestine. Children with this disease must eliminate gluten from their diet. This article provides educators with essential information on celiac disease and the federal laws that protect the rights of these students. A study of the educational and social challenges of children affected by the disease is presented so school personnel are aware of the effects of celiac disease on the school experiences of students in pre-kindergarten through grade 12. In addition, recommendations for the academic environment and school community are provided so school personnel can provide a positive educational experience for children who must eat gluten free.