Background: Respite care is an essential support for people with intellectual disabilities and their families; however, there is limited evidence examining different models of respite care. The present research examined quality of life among adults with intellectual disabilities using three different models of respite services in Ireland. Method: A quasi-experimental research method was adopted, which sought to determine differences in quality of life across the three respite care groups using two measures, (1) a self-reported quality of life scale and (2) a quality of life questionnaire filled out by a keyworker. Participants were people with mild/moderate intellectual disabilities (n = 82) and their keyworkers (n = 81). Results: Three distinct models of respite services were assessed: (a) Traditional- Residential respite; (b) Personalised Residential respite, and (c) Personalised Non-Residential respite. No differences emerged between the groups on self-reported quality of life; however, the groups differed on a proxy measure of quality of life with respect to Rights, emotional well-being, personal development and interpersonal relationships. Conclusion: The current data offer an initial exploration of self- and proxy-reported quality of life among persons with intellectual disabilities in receipt of novel models of respite care in Ireland.