Research in the field of learning disability presents particular ethical challenges when obtaining consent from participants. This is further exacerbated when the nature of the research requires participation at all ability levels and involves people with communication impairments. The process of obtaining consent in a research study with 48 participants at four levels of comprehension ability is discussed in this paper. The specific issues of recruitment, seeking consent, ongoing consent and feedback are detailed as are the adaptations made in this project to research methodology and the accessible methods of communication employed. Implications for researchers and future directions for further studies are presented.