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Problem-Solving Test: Analysis of DNA Damage Recognizing Proteins in Yeast and Human Cells
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2013
The experiment described in this test was aimed at identifying DNA repair proteins in human and yeast cells. Terms to be familiar with before you start to solve the test: DNA repair, germline mutation, somatic mutation, inherited disease, cancer, restriction endonuclease, radioactive labeling, [alpha-[superscript 32]P]ATP, [gamma-[superscript…
Descriptors: Genetics, Science Experiments, Multiple Choice Tests, Problem Solving
Problem-Solving Test: The Role of a Micro-RNA in the Regulation of "fos" Gene Expression
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Szeberenyi, Jozsef – Biochemistry and Molecular Biology Education, 2009
The "fos" proto-oncogene codes for a component of the AP1 transcription factor, an important regulator of gene expression and cell proliferation. Dysregulation of AP1 function may lead to the malignant transformation of the cell. The present test describes an experiment in which the role of a micro-RNA (miR-7b) in the regulation of "fos" gene…
Descriptors: Genetics, Cancer, Role, Molecular Biology