The aim of this research was conducted to determine the effects of Cooperative Integrated Reading and Composition (CIRC) with mind mapping strategy on the student's achievement and motivation of 11th-grade Secondary students in Pekanbaru Indonesia regarding topics related to colloid. This research employed a pre test / post test quasi-experimental design. This study was carried out with two groups, a study group (were instructed using CIRC with mind mapping method) while a control group (approached with conventional teaching method). Data for achievement were collected using Colloid Conceptual test and motivation data were collected using a questionnaire. The data were analyzed used SPSS 20.0 statistic program in term of descriptif, frequency, arithmetic means, and standard deviation. Unclear sentence inferential statistical analysis used t-tests and MANOVA to identify differences in achievement and motivation of the treatment and control groups. The findings show that there are differences in the achievement of students who used Cooperative Integrated Reading and Composition (CIRC) with mind mapping strategy, and no significant difference in motivation. This research has identified a learning strategy that can improve students' achievement in chemistry that needs to be applied, so that they can enhance their learning experience and achievement in chemistry lesson.