This study investigates factors that influence learners' satisfaction with massive open online courses (MOOCs). Framed by the theory of independent learning and teaching, the three types of interaction model, and the technology acceptance model, this study analyzed data collected from 1,786 learners enrolled in four MOOCs. Results show that the learner perceived usefulness, teaching and learning aspects of the MOOC, and learner-content interaction as important satisfaction factors. Learner-learner interaction and learner-instructor interaction had no effect on the sample's learner satisfaction with the MOOC. These findings improve our understanding of MOOC learners' preferences and contribute to the process of designing and developing new MOOCs. Future directions in MOOCs' development are also discussed.