Phylogenetic tree diagrams are commonly found in introductory biology curricula and represent the evolutionary relationships of organisms. Tree-thinking, or the ability to accurately interpret, use, and generate these phylogenetic representations, involves a challenging set of skills for students to learn. Although many introductory biology…

Modeling is a core practice in science and is a meaningful way to learn the subject. This article introduces a modeling-based approach that highlights the idea that modeling is an iterative process and integrates the fundamental parts of scientists' work and key suggestions for teaching through modeling. The lesson "The Structure and Function…

Despite critical thinking supporting a deeper understanding of the scientific process, university activities prioritize lower cognitive processes, such as remembering skills. Also, it is unclear whether gender biases in interest toward science exist in university science degrees. These hinder students from achieving their goals effectively since…

Biological interactions and associations underlie life's processes at every level of organization. Here, we present a classroom activity that allows students to visualize and understand the connections within almost any biological system, from cell functions to ecological relationships. We recommend that instructors implement this activity to…

One of the important mechanisms in cancer cell metastasis is the cellular function of a specific cell type called myofibroblast cells. Myofibroblast cells are unique cell types that play an important role in the cancer cell microenvironment. As a step toward integrating the latest peer-reviewed cancer research findings into a general biology…

The use of virtual reality (VR) as a medium for education can contribute to the learning efficiency of students. This study aimed to assess the effectiveness of VR application in advanced biology courses, specifically in enhancing the comprehension and understanding of high school students toward the topic of human organs and other related…

This study aimed to compare the effects of computer-based lessons versus traditional lessons on achievement of university students regarding meiotic cell division. A pretest-intervention-posttest design was used. To determine the effect of our computer-based intervention, we established a control group. In total, 100 second-year university…

Concepts relating to enzymes and energy are central to understanding chemical and biological processes at the molecular level. Student learning of these crosscutting concepts can be challenging, so it is important to identify misconceptions and remediate them early, especially in introductory classes. Here we describe an activity in which…

Large data sets invite students to engage in scientific practices such as question asking, identifying correlations, using visualizations, and practicing data literacy in an authentic context. However, authentic data sets are rarely introduced in the biology classroom. We prepared an online inquiry activity based on authentic gross characteristics…

The United States still has one of the lowest evolution acceptance rates in the world. Biology educators have been diligent in their methods to increase evolution acceptance and knowledge, with much success. However, misconceptions still arise through education, textbooks, and even social and religious settings that may influence our citizens' low…

Evolutionary medicine is a growing area of research and practice; however, it is not widely discussed in introductory biology courses. Because of the interest in human biology, using evolutionary medicine is a great way to hold students' interest, placing topics in context, making the subject of evolution relevant. Too often students lose interest…

There is an emphasis on survival-based selection in biology education that can allow students to neglect other important evolutionary components, such as sexual selection, reproduction, and inheritance. Student understanding of the role of reproduction in evolution is as important as student understanding of the role of survival. Limiting…

Case studies are valuable tools for instruction but are often limited to a single topic and a single class period. Courses such as evolution that synthesize multiple concepts around a common theme, however, can use a single case study type project that extends over the entire semester to develop and link core concepts. A central theme in…

The discovery of and research into penicillin resistance by Sir Edward Abraham and Sir Ernst Chain can be used to teach the concept of natural selection and also multiple nature of science (NOS) objectives associated with Next Generation Science Standards, such as "scientific knowledge is based on empirical evidence" and "science is…

Organismal biology (OrgBio) comprises the diversity, structures, and functions of all organisms from bacteria to humans. Arguably, OrgBio is often the most poorly taught and least conceptually rigorous section of the introductory biology sequence offered at most U.S. institutions of higher education. This article reports on the successful…