Young people of color and young people growing up in low-income communities are at high risk for experiencing poor health. In part, this is because they have inequitable access to the supports, opportunities, and experiences that science affirms are essential for children's well-being. Wellness initiatives--holistic approaches to overall physical and psychological health--offer promising prevention-focused health strategies. Wellness approaches are less common, however, in communities of color. At the same time, youth of color are the fastest-growing segment of the child population in the U.S. Therefore, identifying promising practices to improve the health and well-being of young people of color and young people in low-income communities is critical to the vitality of our nation. To align policies and practices with young people's lived experiences, decision-makers need to hear from young people themselves. Yet engaging young people in health-related research, policy, or recommended practices is an approach that has not been widely used or studied in the public health field. To better understand the obstacles to well-being experienced by young people of color in low-income urban communities, the Center for Promise (CfP) implemented a youth-led health and wellness assessment in five cities--Boston, Chicago, Denver, Philadelphia, and St. Paul. This report summarizes findings from the youth-led assessment, bringing young people's voices and views into the discussion about what affects their health and wellness. [Dr. Jonathan Zaff, Craig McClay, and Catalina Tang served as co-investigators. For the full report, see ED572744.]