In this article Liz O'Brien discusses the need for a distinctive approach to the religious education of children and young people with autism and/or severe and complex learning disabilities. She describes how an imaginative and creative approach, built on an underlying principle of understanding, empathy and respect in relation to the culture of autism can lead to enriching, meaningful and enjoyable RE experiences. Through an RE and Special Needs Fellowship, awarded by the National Society for Promoting Christian Education, she was given the opportunity to assemble Connecting with RE (O'Brien, 2002), a resource for all those seeking accessible RE for children with autism and/or severe and complex learning disabilities. This article presents some of the fundamental philosophy and methodology that underpin the Connecting with RE approach.