A wide range of conditions in the places where children live, grow, play, and learn can get "under the skin" and affect their developing brains and other biological systems. Rapidly advancing science around early childhood development provides increasingly clear evidence that, beginning before birth, these environmental conditions shape…

We know that responsive relationships and language-rich experiences for young children help build a strong foundation for later success in school. The rapidly advancing frontiers of 21st-century biological sciences now provide compelling evidence that the foundations of lifelong health are also built early, with increasing evidence of the…

A healthy, engaged community depends on people achieving to the best of their potential, contributing actively to the economy and public well-being, and helping the next generation to thrive. A complex set of intertwined social and biological factors influences people's motivation to participate actively and productively in schools, jobs, and…

Young children who experience severe deprivation or neglect can experience a range of negative consequences. Neglect can delay brain development, impair executive function skills, and disrupt the body's stress response. This working paper from the National Scientific Council on the Developing Child explains why neglect is so harmful in the…

Being able to focus, hold, and work with information in mind, filter distractions, and switch gears is like having an air traffic control system at a busy airport to manage the arrivals and departures of dozens of planes on multiple runways. In the brain, this air traffic control mechanism is called executive functioning, a group of skills that…

Ensuring that young children have safe, secure environments in which to grow, learn, and develop healthy brains and bodies is not only good for the children themselves but also builds a strong foundation for a thriving, prosperous society. Science shows that early exposure to circumstances that produce persistent fear and chronic anxiety can have…

New scientific research shows that environmental influences can actually affect whether and how genes are expressed. Thus, the old ideas that genes are "set in stone" or that they alone determine development have been disproven. In fact, scientists have discovered that early experiences can determine how genes are turned on and off and even…

Significant mental health problems can and do occur in young children. In some cases, these problems can have serious consequences for early learning, social competence, and lifelong health. Furthermore, the foundations of many mental health problems that endure through adulthood are established early in life through the interaction of genetic…

This brief describes the findings of a study that tested preschoolers' executive function skills after participating in a program designed to enhance them vs. a standard curriculum. A total of 147 5-year-olds in their second year of preschool from a lower-income, urban school district participated in this study. The preschoolers were in 18…

This brief presents the findings of a study that examined the effects of "allostatic load" on children in poverty at age 9 and 13. "Allostatic load" refers to the measurement of the cumulative wear and tear on the body that results from experiencing stress. Research shows that high allostatic load in childhood is associated with long-term…

"Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This brief reports on the study "Attention-deficit/Hyperactivity Disorder is Characterized by a Delay in Cortical Maturation" (P. Shaw; K. Eckstrand; W. Sharp; J. Blumenthal; J. P. Lerch; D. Greenstein; L. Clasen; A. Evans; J. Giedd;…

"Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This brief reports on the study "Effects of Prenatal Alcohol Exposure on GABAergic Neurons" (V. C. Cuzone; P. W. L. Yeh; Y. Yanagawa; K. Obata; and H. H. Yeh). Study results indicate that even exposure to low levels of alcohol during…

The foundations of brain architecture are established early in life through a continuous series of dynamic interactions in which environmental conditions and personal experiences have a significant impact on how genetic predispositions are expressed. Because specific experiences affect specific brain circuits during specific developmental…

"Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This brief reports on the study "Are there Long-Term Effects of Early Child Care?" (J. Belsky, D. L. Vandell, M. Burchinal, K. A. Clarke-Stewart, K. McCartney, M. T. Owen, M. T., and The NICHD Early Child Care Research Network).…

"Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This brief reports on the study "Mother-Child Bookreading in Low-Income Families: Correlates and Outcomes during the First Three Years of Life" (H. Raikes, B. A. Pan, G. Luze, C. S. Tamis-LeMonda, J. Brooks-Gunn, J. Constantine, L. B.…