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Showing 1 to 15 of 3,329 results Save | Export
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Gebhardt, Christine; Albrecht, Doris – Learning & Memory, 2018
Capsaicin has been shown to modulate synaptic plasticity in various brain regions including the amygdala. Whereas in the lateral amygdala the modulatory effect of capsaicin on long-term potentiation (LA-LTP) is mediated by TRPV1 channels, we have recently shown that capsaicin-induced enhancement of long term depression (LA-LTD) is mediated by…
Descriptors: Memory, Brain Hemisphere Functions, Depression (Psychology), Animals
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Foilb, Allison R.; Bals, Julia; Sarlitto, Mary C.; Christianson, John P. – Learning & Memory, 2018
Distinguishing safety from danger is necessary for survival, but is aberrant in individuals with post-traumatic stress disorder (PTSD). While PTSD is more prevalent in women than men, research on sex differences in safety learning is limited. Here, female rats demonstrated greater fear discrimination than males in a CS+/CS- paradigm. To determine…
Descriptors: Gender Differences, Posttraumatic Stress Disorder, Fear, Discrimination Learning
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Matell, Matthew S.; Della Valle, Rebecca B. – Learning & Memory, 2018
Presentation of a previously trained Pavlovian conditioned stimulus while an organism is engaged in operant responding can moderate the rate of responding, a phenomenon known as Pavlovian-to-instrumental transfer. Although it is well known that Pavlovian contingencies will generate conditioned behavior that is temporally organized with respect to…
Descriptors: Operant Conditioning, Experiments, Animals, Time
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Perez, Leticia; Patel, Ushma; Rivota, Marissa; Calin-Jageman, Irina E.; Calin-Jageman, Robert J. – Learning & Memory, 2018
Most long-term memories are forgotten. What happens, then, to the changes in neuronal gene expression that were initially required to encode and maintain the memory? Here we show that the decay of recall for long-term sensitization memory in "Aplysia" is accompanied both by a form of savings memory (easier relearning) and by persistent…
Descriptors: Long Term Memory, Genetics, Recall (Psychology), Animals
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Vogel, Susanne; Kluen, Lisa Marieke; Fernández, Guillén; Schwabe, Lars – Learning & Memory, 2018
Prior knowledge, represented as a mental schema, has critical impact on how we organize, interpret, and process incoming information. Recent findings indicate that the use of an existing schema is coordinated by the medial prefrontal cortex (mPFC), communicating with parietal areas. The hippocampus, however, is crucial for encoding…
Descriptors: Stress Variables, Brain Hemisphere Functions, Cognitive Processes, Schemata (Cognition)
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Newsome, Rachel N.; Trelle, Alexandra N.; Fidalgo, Celia; Hong, Bryan; Smith, Victoria M.; Jacob, Alexander; Ryan, Jennifer D.; Rosenbaum, R. Shayna; Cowell, Rosemary A.; Barense, Morgan D. – Learning & Memory, 2018
The thalamic nuclei are thought to play a critical role in recognition memory. Specifically, the anterior thalamic nuclei and medial dorsal nuclei may serve as critical output structures in distinct hippocampal and perirhinal cortex systems, respectively. Existing evidence indicates that damage to the anterior thalamic nuclei leads to impairments…
Descriptors: Memory, Recognition (Psychology), Brain Hemisphere Functions, Neurological Impairments
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Briskin-Luchinsky, Valeria; Levy, Roi; Halfon, Maayan; Susswein, Abraham J. – Learning & Memory, 2018
Training "Aplysia" with inedible food for a period that is too brief to produce long-term memory becomes effective in producing memory when training is paired with a nitric oxide (NO) donor. Lip stimulation for the same period of time paired with an NO donor is ineffective. Using qPCR, we examined molecular correlates of brief training…
Descriptors: Animals, Training, Food, Long Term Memory
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Smedley, Elizabeth B.; Smith, Kyle S. – Learning & Memory, 2018
Sign-tracking is a form of autoshaping where animals develop conditioned responding directed toward stimuli predictive of an outcome even though the outcome is not contingent on the animal's behavior. Sign-tracking behaviors are thought to arise out of the attribution of incentive salience (i.e., motivational value) to reward-predictive cues. It…
Descriptors: Cues, Rewards, Persistence, Responses
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Atlas, Lauren Y.; Phelps, Elizabeth A. – Learning & Memory, 2018
Fear-relevant stimuli such as snakes and spiders are thought to capture attention due to evolutionary significance. Classical conditioning experiments indicate that these stimuli accelerate learning, while instructed extinction experiments suggest they may be less responsive to instructions. We manipulated stimulus type during instructed aversive…
Descriptors: Fear, Stimuli, Hypothesis Testing, Visual Stimuli
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Mei, Hao; Logothetis, Nikos K.; Eschenko, Oxana – Learning & Memory, 2018
Spatial navigation depends on the hippocampal function, but also requires bidirectional interactions between the hippocampus (HPC) and the prefrontal cortex (PFC). The cross-regional communication is typically regulated by critical nodes of a distributed brain network. The thalamic nucleus reuniens (RE) is reciprocally connected to both HPC and…
Descriptors: Spatial Ability, Brain Hemisphere Functions, Animals, Memory
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Baggett, Vincent; Mishra, Aditi; Kehrer, Abigail L.; Robinson, Abbey O.; Shaw, Paul; Zars, Troy – Learning & Memory, 2018
Animals in a natural environment confront many sensory cues. Some of these cues bias behavioral decisions independent of experience, and action selection can reveal a stimulus-response (S-R) connection. However, in a changing environment it would be a benefit for an animal to update behavioral action selection based on experience, and learning…
Descriptors: Cues, Stimuli, Animal Behavior, Entomology
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Viczko, Jeremy; Sergeeva, Valya; Ray, Laura B.; Owen, Adrian M.; Fogel, Stuart M. – Learning & Memory, 2018
Sleep facilitates the consolidation (i.e., enhancement) of simple, explicit (i.e., conscious) motor sequence learning (MSL). MSL can be dissociated into egocentric (i.e., motor) or allocentric (i.e., spatial) frames of reference. The consolidation of the allocentric memory representation is sleep-dependent, whereas the egocentric consolidation…
Descriptors: Sleep, Memory, Visual Perception, Psychomotor Skills
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McHail, Daniel G.; Valibeigi, Nazanin; Dumas, Theodore C. – Learning & Memory, 2018
The neural bases of cognition may be greatly informed by relating temporally defined developmental changes in behavior with concurrent alterations in neural function. A robust improvement in performance in spatial learning and memory tasks occurs at 3 wk of age in rodents. We reported that the developmental increase of spontaneous alternation in a…
Descriptors: Spatial Ability, Memory, Animals, Brain Hemisphere Functions
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Snow, Wanda M.; Cadonic, Chris; Cortes-Perez, Claudia; Chowdhury, Subir K. Roy; Djordjevic, Jelena; Thomson, Ella; Bernstein, Michael J.; Suh, Miyoung; Fernyhough, Paul; Albensi, Benedict C. – Learning & Memory, 2018
The brain has a high demand for energy, of which creatine (Cr) is an important regulator. Studies document neurocognitive benefits of oral Cr in mammals, yet little is known regarding their physiological basis. This study investigated the effects of Cr supplementation (3%, w/w) on hippocampal function in male C57BL/6 mice, including spatial…
Descriptors: Energy, Brain Hemisphere Functions, Animals, Spatial Ability
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Westerberg, Carmen E.; Hawkins, Christopher A.; Rendon, Lauren – Learning & Memory, 2018
Reality-monitoring errors occur when internally generated thoughts are remembered as external occurrences. We hypothesized that sleep-dependent memory consolidation could reduce them by strengthening connections between items and their contexts during an afternoon nap. Participants viewed words and imagined their referents. Pictures of the…
Descriptors: Sleep, Memory, Hypothesis Testing, Visual Stimuli
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