The classroom-friendly ABO blood type kit was developed by combining advantages of modelling and a simulation laboratory to teach the topics of ABO blood types and blood transfusion. Teachers can easily simulate the agglutination reaction on a blood type testing plate in the classroom, and show the students how this reaction occurs by using the models. Simple materials are used to help teachers prepare for daily teaching. The kit can be used to engage students in hands-on and minds-on activities. There were some positive preliminary results reported after using the kit with Thai high-school students. (Contains 2 tables and 6 figures.)