ERIC Number: EJ1182069
Record Type: Journal
Publication Date: 2018-Jul
Abstractor: As Provided
Investigating Mirror System (MS) Activity in Adults with ASD When Inferring Others' Intentions Using Both TMS and EEG
Cole, Eleanor J.; Barraclough, Nick E.; Enticott, Peter G.
Journal of Autism and Developmental Disorders, v48 n7 p2350-2367 Jul 2018
ASD is associated with mentalizing deficits that may correspond with atypical mirror system (MS) activation. We investigated MS activity in adults with and without ASD when inferring others' intentions using TMS-induced motor evoked potentials (MEPs) and mu suppression measured by EEG. Autistic traits were measured for all participants. Our EEG data show, high levels of autistic traits predicted reduced right mu (8-10 Hz) suppression when mentalizing. Higher left mu (8-10 Hz) suppression was associated with superior mentalizing performances. Eye-tracking and TMS data showed no differences associated with autistic traits. Our data suggest ASD is associated with reduced right MS activity when mentalizing, TMS-induced MEPs and mu suppression measure different aspects of MS functioning and the MS is directly involved in inferring intentions.
Descriptors: Autism, Pervasive Developmental Disorders, Adults, Social Cognition, Cognitive Processes, Schemata (Cognition), Inferences, Intention, Measurement Equipment, Eye Movements, Asperger Syndrome, Foreign Countries, Diagnostic Tests, Observation, Multivariate Analysis
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: Australia
Identifiers - Assessments and Surveys: Autism Diagnostic Observation Schedule