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ERIC Number: EJ921596
Record Type: Journal
Publication Date: 2011-Jan
Pages: 4
Abstractor: As Provided
ISSN: ISSN-0021-9584
Representing Rate Equations for Enzyme-Catalyzed Reactions
Ault, Addison
Journal of Chemical Education, v88 n1 p63-66 Jan 2011
Rate equations for enzyme-catalyzed reactions are derived and presented in a way that makes it easier for the nonspecialist to see how the rate of an enzyme-catalyzed reaction depends upon kinetic constants and concentrations. This is done with distribution equations that show how the rate of the reaction depends upon the relative quantities of the various enzyme species in the reaction mixture. The first three examples are from the article published by Sims in this "Journal": the one-substrate no-inhibitor reaction, the one-substrate competitive-inhibition reaction, and the two-substrate ordered reaction. This approach is then extended to the two-substrate rapid-equilibrium reaction and the two-substrate ping-pong reaction.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A