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Direct linkMolina, Brooke S. G.; Hinshaw, Stephen P.; Swanson, James W.; Arnold, L. Eugene; Vitiello, Benedetto; Jensen, Peter S.; Epstein, Jeffery N.; Hoza, Betsy; Hechtman, Lily; Abikoff, Howard B.; Elliott, Glen R.; Greenhill, Laurence L.; Newcorn, Jeffrey H.; Wells, Karen C.; Wigal, Timothy; Gibbons, Robert D.; Hur, Kwan; Houck, Patricia R. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Participants of the Multimodal Treatment Study of Children with Attention Deficit and Hyperactivity Disorder (ADHD) eight years earlier do not differ significantly in repeated measures or newly analyzed variables that include school grades and psychiatric hospitalization. The treatment of childhood ADHD does not predict functioning six to eight…
Descriptors: Attention Deficit Hyperactivity Disorder, Children, Hospitalized Children, Followup Studies
Harty, Seth C.; Miller, Carlin J.; Newcorn, Jeffrey H.; Halperin, Jeffrey M. – Child Psychiatry and Human Development, 2009
This study examined the self-reported expression of overt aggressive behaviors and covert emotional and cognitive processes in adolescents diagnosed with ADHD and comorbid disruptive behavior disorders (DBDs) during childhood. Methods: Participants were a clinically referred sample of 85 individuals diagnosed with ADHD, initially recruited in the…
Descriptors: Aggression, Hyperactivity, Behavior Disorders, Identification
Peer reviewedSchulz, Kurt P.; Newcorn, Jeffrey H.; Fan, Jin; Tang, Cheuk Y.; Halperin, Jeffrey M. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To explore the possible role that functional abnormalities of the prefrontal cortex and basal ganglia play in the persistence of attention-deficit/hyperactivity disorder (ADHD) in adolescents aged 15 to 19 years. Method: Ten male adolescents who were diagnosed with ADHD during childhood were grouped into those who continued to meet full…
Descriptors: Psychiatry, Persistence, Adolescents, Hyperactivity
Peer reviewedNewcorn, Jeffrey H.; Spencer, Thomas J.; Biederman, Joseph; Milton, Denai R.; Michelson, David – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To examine (1) moderating effects of oppositional defiant disorder (ODD) on attention-deficit/hyperactivity disorder (ADHD) treatment response and (2) responses of ODD symptoms to atomoxetine. Method: Children and adolescents (ages 8-18) with ADHD were treated for approximately 8 weeks with placebo or atomoxetine (fixed dosing: 0.5,…
Descriptors: Psychiatry, Patients, Child Health, Adolescents
Halperin, Jeffrey M.; Trampush, Joey W.; Miller, Carlin J.; Marks, David J.; Newcorn, Jeffrey H. – Journal of Child Psychology and Psychiatry, 2008
Background: This study examined neuropsychological functioning in a longitudinal sample of adolescents/young adults with attention deficit/hyperactivity disorder (ADHD) and controls as a function of the persistence of ADHD. We hypothesized that measures of executive processes would parallel adolescent clinical status, with ADHD-persisters, but not…
Descriptors: Attention Deficit Disorders, Hyperactivity, Young Adults, Adolescents
Nomura, Yoko; Rajendran, Khushmand; Brooks-Gunn, Jeanne; Newcorn, Jeffrey H. – Journal of Child Psychology and Psychiatry, 2008
Background: There is uncertainty about the extent to which mildly sub-optimal perinatal characteristics among individuals born near-term (greater than 33 weeks of gestation) are associated with various subsequent childhood problems, including antisocial behavior. There is even more uncertainty about whether the pathway to antisocial behavior…
Descriptors: Antisocial Behavior, Structural Equation Models, Academic Achievement, Pregnancy
Newcorn, Jeffrey H.; Sutton, Virginia K.; Zhang, Shuyu; Wilens, Timothy; Kratochvil, Christopher; Emslie, Graham J.; D'Souza, Deborah N.; Schuh, Leslie M.; Allen, Albert J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Objective: Understanding placebo response is a prerequisite to improving clinical trial methodology. Data from placebo-controlled trials of atomoxetine in the treatment of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) were analyzed to identify demographic and clinical characteristics that might predict placebo…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Rating Scales, Patients
Newcorn, Jeffrey H.; Sutton, Virginia K.; Weiss, Margaret D.; Sumner, Calvin R. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Data from six randomized controlled trials in the U.S. reveal that 47 percent of patients aged six to 18 years showed a much improved clinical response to atomoxetine as a treatment for attention deficit hyperactivity disorder while 40 percent did not have a response. Augmenting or switching treatment in non-responders by week 4 is suggested.
Descriptors: Attention Deficit Hyperactivity Disorder, Drug Therapy, Patients, Children
Papadopulos, Elizabeth; Jensen, Peter S.; Chait, Alanna R.; Arnold, L. Eugene; Swanson, James M.; Greenhill, Laurence L.; Hechtman, Lily; Chuang, Shirley; Wells, Karen C.; Pelham, William; Cooper, Thomas; Elliott, Glenn; Newcorn, Jeffrey H. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Saliva methylphenidate samples from participants in the Multimodal Treatment Study of Children with Attention Deficit and Hyperactivity Disorder reveal that nearly half of them had some degree of nonadherence to treatment. This suggests that nearly half of the parent reports of medication use are inaccurate.
Descriptors: Drug Therapy, Attention Deficit Hyperactivity Disorder, Compliance (Psychology), Children
Epstein, Jeffery N.; Conners, C. Keith; Hervey, Aaron S.; Tonev, Simon T.; Arnold, L. Eugene; Abikoff, Howard B.; Elliott, Glen; Greenhill, Laurence L.; Hechtman, Lily; Hoagwood, Kimberly; Hinshaw, Stephen P.; Hoza, Betsy; Jensen, Peter S.; March, John S.; Newcorn, Jeffrey H.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen; Vitiello, Benedetto; Wigal, Timothy – Journal of Child Psychology and Psychiatry, 2006
Background: While studies have increasingly investigated deficits in reaction time (RT) and RT variability in children with attention deficit/hyperactivity disorder (ADHD), few studies have examined the effects of stimulant medication on these important neuropsychological outcome measures. Methods: 316 children who participated in the Multimodal…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Reaction Time, Drug Therapy
Swanson, James M.; Hinshaw, Stephen P.; Arnold, L. Eugene; Gibbons, Robert D.; Marcus, Sue; Hur, Kwan; Jensen, Peter S.; Vitiello, Benedetto; Abikoff, Howard B.: Greenhill, Laurence L.; Hechtman, Lily; Pelham, William E.; Wells, Karen C.; Conners, C. Keith; March, John S.; Elliott, Glen R.; Epstein, Jeffery N.; Hoagwood, Kimberly; Hoza, Betsy; Molina, Brooke S. G.; Newcorn, Jeffrey H.; Severe, Joanne B.; Wigal, Timothy – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To evaluate two hypotheses: that self-selection bias contributed to lack of medication advantage at the 36-month assessment of the Multimodal Treatment Study of Children With ADHD (MTA) and that overall improvement over time obscured treatment effects in subgroups with different outcome trajectories. Method: Propensity score analyses,…
Descriptors: Attention Deficit Hyperactivity Disorder, Research Methodology, Evaluation Methods, Models
Swanson, James M.; Elliott, Glen R.; Greenhill, Laurence L.; Wigal, Timothy; Arnold, L. Eugene; Vitiello, Benedetto; Hechtman, Lily; Epstein, Jeffery N.; Pelham, William E.; Abikoff, Howard B.; Newcorn, Jeffrey H.; Molina, Brooke S. G.; Hinshaw, Stephen P.; Wells, Karen C.; Hoza, Betsy; Jensen, Peter S.; Gibbons, Robert D.; Hur, Kwan; Stehli, Annamarie; Davies, Mark; March, John S.; Conners, C. Keith; Caron, Mark; Volkow, Nora D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD. Method: Naturalistic subgroups were established based on patterns of treatment with stimulant medication at baseline, 14-, 24-, and 36-month assessments: not medicated (n = 65),…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Norms, Statistical Analysis
Molina, Brooke S. G.; Flory, Kate; Hinshaw, Stephen P.; Greiner, Andrew R.; Arnold, L. Eugene; Swanson, James M.; Hechtman, Lily; Jensen, Peter S.; Vitiello, Benedetto; Hoza, Betsy; Pelham, William E.; Elliott, Glen R.; Wells, Karen C.; Abikoff, Howard B.; Gibbons, Robert D.; Marcus, Sue; Conners, C. Keith; Epstein, Jeffery N.; Greenhill, Laurence L.; March, John S.; Newcorn, Jeffrey H.; Severe, Joanne B.; Wigal, Timothy – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To compare delinquent behavior and early substance use between the children in the Multimodal Treatment Study of Children With ADHD (MTA; N = 487) and those in a local normative comparison group (n = 272) at 24 and 36 months postrandomization and to test whether these outcomes were predicted by the randomly assigned treatments and…
Descriptors: Attention Deficit Hyperactivity Disorder, Delinquency, Behavior Modification, Therapy
Jensen, Peter S.; Arnold, L. Eugene; Swanson, James M.; Vitiello, Benedetto; Abikoff, Howard B.; Greenhill, Laurence L.; Hechtman, Lily; Hinshaw, Stephen P.; Pelham, William E.; Wells, Karen C.; Conners, C. Keith; Elliott, Glen R.; Epstein, Jeffery N.; Hoza, Betsy; March, John S.; Molina, Brooke S. G.; Newcorn, Jeffrey H.; Severe, Joanne B.; Wigal, Timothy; Gibbons, Robert D.; Hur, Kwan – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: In the intent-to-treat analysis of the Multimodal Treatment Study of Children With ADHD (MTA), the effects of medication management (MedMgt), behavior therapy (Beh), their combination (Comb), and usual community care (CC) differed at 14 and 24 months due to superiority of treatments that used the MTA medication algorithm (Comb+MedMgt)…
Descriptors: Attention Deficit Hyperactivity Disorder, Behavior Modification, Psychopathology, Therapy
Kratochvil, Christopher J.; Michelson, David; Newcorn, Jeffrey H.; Weiss, Margaret D.; Busner, Joan; Moore, Rodney J.; Ruff, Dustin D.; Ramsey, Janet; Dickson, Ruth; Turgay, Atilla; Saylor, Keith E.; Luber, Stephen; Vaughan, Brigette; Allen, Albert J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To assess the utility and tolerability of higher than standard atomoxetine doses to treat attention-deficit/hyperactivity disorder (ADHD). Method: Two randomized, double-blind trials of atomoxetine nonresponders ages 6 to 16 years were conducted comparing continued treatment with same-dose atomoxetine to treatment using greater than…
Descriptors: Hyperactivity, Attention Deficit Disorders, Rating Scales, Patients
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