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Showing 16 to 30 of 191 results Save | Export
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Jarome, Timothy J.; Kwapis, Janine L.; Werner, Craig T.; Parsons, Ryan G.; Gafford, Georgette M.; Helmstetter, Fred J. – Learning & Memory, 2012
Numerous studies have indicated that maintaining a fear memory after retrieval requires de novo protein synthesis. However, no study to date has examined how the temporal dynamics of repeated retrieval events affect this protein synthesis requirement. The present study varied the timing of a second retrieval of an established auditory fear memory…
Descriptors: Genetics, Program Effectiveness, Long Term Memory, Fear
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Hegde, Ashok N.; Smith, Spencer G. – Learning & Memory, 2019
Formation of long-term synaptic plasticity that underlies long-term memory requires new protein synthesis. Years of research has elucidated some of the transcriptional and translational mechanisms that contribute to the production of new proteins. Early research on transcription focused on the transcription factor cAMP-responsive element binding…
Descriptors: Memory, Brain Hemisphere Functions, Biochemistry, Molecular Structure
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Jalil, Sajiya J.; Sacktor, Todd Charlton; Shouval, Harel Z. – Learning & Memory, 2015
Memories that last a lifetime are thought to be stored, at least in part, as persistent enhancement of the strength of particular synapses. The synaptic mechanism of these persistent changes, late long-term potentiation (L-LTP), depends on the state and number of specific synaptic proteins. Synaptic proteins, however, have limited dwell times due…
Descriptors: Long Term Memory, Brain Hemisphere Functions, Neurological Organization, Maintenance
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Fischbach, Soren; Kopec, Ashley M.; Carew, Thomas J. – Learning & Memory, 2014
Mechanistically distinct forms of long-lasting plasticity and memory can be induced by a variety of different training patterns. Although several studies have identified distinct molecular pathways that are engaged during these different training patterns, relatively little work has explored potential interactions between pathways when they are…
Descriptors: Inhibition, Memory, Neurological Organization, Training Methods
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Sengupta, Sibani – American Biology Teacher, 2013
RNA interference (abbreviated RNAi) is a relatively new discovery in the field of mechanisms that serve to regulate gene expression (a.k.a. protein synthesis). Gene expression can be regulated at the transcriptional level (mRNA production, processing, or stability) and at the translational level (protein synthesis). RNAi acts in a gene-specific…
Descriptors: Genetics, Science Instruction, High School Students, Secondary School Science
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Anithasri, Anbalagan – Biochemistry and Molecular Biology Education, 2020
Hormones are the major signaling molecules that have a complex signaling cascade involving intracellular and intranuclear receptors, coreceptors, and signal transduction pathways. The molecular mechanism of hormonal action is written in a poetic verse to kindle the interest of students and to augment their affinity toward the onerous yet awesome…
Descriptors: Genetics, Biochemistry, Molecular Structure, Cytology
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Kragten, Marco; Admiraal, Wilfried; Rijlaarsdam, Gert – Journal of Biological Education, 2015
Process diagrams are important tools in biology for explaining processes such as protein synthesis, compound cycles and the like. The aim of the present study was to measure the ability to solve process-diagram problems in biology and its relationship with prior knowledge, spatial ability and working memory. For this purpose, we developed a test…
Descriptors: Secondary School Science, Biology, Problem Solving, Cognitive Ability
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Papper, Marc; Kempter, Richard; Leibold, Christian – Learning & Memory, 2011
Long-term synaptic plasticity exhibits distinct phases. The synaptic tagging hypothesis suggests an early phase in which synapses are prepared, or "tagged," for protein capture, and a late phase in which those proteins are integrated into the synapses to achieve memory consolidation. The synapse specificity of the tags is consistent with…
Descriptors: Genetics, Memory, Rewards, Cognitive Processes
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Chang, Pei-Shan; Lee, Sheng-Han; Wen, Meichun Lydia – Journal of Biological Education, 2020
The central dogma of biology is difficult to learn because its microscopic processes cannot be visualized. This study aimed to devise two inquiry activities: 'Button Code' and 'Beaded Bracelet Making,' involving the concepts of DNA replication and protein synthesis based on the Metacognitive Learning Cycle (MLC) for students, and to explore the…
Descriptors: Metacognition, Inquiry, Active Learning, Biology
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Gungor, Sema Nur; Ozkan, Muhlis – European Journal of Educational Research, 2017
This study examines the subjects and concepts in biology perceived to be difficult to learn and teach by 759 pre-service biology teachers registered in the pedagogical formation program at Uludag University Faculty of Education in the academic year of 2005-2016, as well as the associations that word "biology" first calls to their mind.…
Descriptors: Science Instruction, Genetics, Classification, Teaching Methods
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Zhang, Yili; Smolen, Paul; Baxter, Douglas A.; Byrne, John H. – Learning & Memory, 2010
Memory consolidation and reconsolidation require kinase activation and protein synthesis. Blocking either process during or shortly after training or recall disrupts memory stabilization, which suggests the existence of a critical time window during which these processes are necessary. Using a computational model of kinase synthesis and…
Descriptors: Inhibition, Genetics, Memory, Brain
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Almeida-Corrêa, Suellen; Moulin, Thiago C.; Carneiro, Clarissa F. D.; Gonçalves, Marina M. C.; Junqueira, Lara S.; Amaral, Olavo B. – Learning & Memory, 2015
Memory extinction involves the formation of a new associative memory that inhibits a previously conditioned association. Nonetheless, it could also depend on weakening of the original memory trace if extinction is assumed to have multiple components. The phosphatase calcineurin (CaN) has been described as being involved in extinction but not in…
Descriptors: Memory, Animals, Fear, Learning Processes
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Thörne, Karin; Gericke, Niklas – Research in Science Education, 2014
This study investigates Swedish biology teachers' inclusion of proteins when teaching genetics in grade nine (students 15-16 years old). For some years, there has been a call to give attention to proteins when teaching genetics as a means of linking the concepts "gene" and "trait". Students are known to have problems with this…
Descriptors: Genetics, Science Instruction, Teaching Methods, Verbal Communication
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Colettis, Natalia C.; Snitcofsky, Marina; Kornisiuk, Edgar E.; Gonzalez, Emilio N.; Quillfeldt, Jorge A.; Jerusalinsky, Diana A. – Learning & Memory, 2014
The muscarinic cholinergic receptor (MAChR) blockade with scopolamine either extended or restricted to the hippocampus, before or after training in inhibitory avoidance (IA) caused anterograde or retrograde amnesia, respectively, in the rat, because there was no long-term memory (LTM) expression. Adult Wistar rats previously exposed to one or two…
Descriptors: Memory, Neurological Impairments, Inhibition, Brain
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Langille, Jesse J.; Ginzberg, Keren; Sossin, Wayne S. – Learning & Memory, 2019
In neurons, mRNAs can be repressed postinitiation and assembled into granules enabling the transport and later, regulated reactivation of the paused mRNAs. It has been suggested that a large percentage of transcripts in neuronal processes are stored in these stalled polysomes. Given this, it is predicted that nascent peptides should be abundant in…
Descriptors: Brain Hemisphere Functions, Genetics, Biochemistry, Prediction
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