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Salamone, John D.; Correa, Merce; Nunes, Eric J.; Randall, Patrick A.; Pardo, Marta – Journal of the Experimental Analysis of Behavior, 2012
For many years, it has been suggested that drugs that interfere with dopamine (DA) transmission alter the "rewarding" impact of primary reinforcers such as food. Research and theory related to the functions of mesolimbic DA are undergoing a substantial conceptual restructuring, with the traditional emphasis on hedonia and primary reward yielding…
Descriptors: Pharmacology, Drug Use, Biochemistry, Reinforcement
Villarreal, Ronald P.; Steinmetz, Joseph E. – Journal of the Experimental Analysis of Behavior, 2005
How the nervous system encodes learning and memory processes has interested researchers for 100 years. Over this span of time, a number of basic neuroscience methods has been developed to explore the relationship between learning and the brain, including brain lesion, stimulation, pharmacology, anatomy, imaging, and recording techniques. In this…
Descriptors: Brain Hemisphere Functions, Anatomy, Brain, Associative Learning
Rebec, George V.; Sun, WenLin – Journal of the Experimental Analysis of Behavior, 2005
The return to drug seeking, even after prolonged periods of abstinence, is a defining feature of cocaine addiction. The neural circuitry underlying relapse has been identified in neuropharmacological studies of experimental animals, typically rats, and supported in brain imaging studies of human addicts. Although the nucleus accumbens (NAcc),…
Descriptors: Addictive Behavior, Neurology, Cues, Cocaine