This article considers the validity and factorial invariance of an attitudinal measure of familism. Using a large, nationally representative sample of U.S. Hispanics, the validity and factorial invariance of the measure was tested across country of origin (United States, Mexico, and Latin America) and the language in which the survey was conducted (Spanish and English). Results support the invariance of the measure in both group comparisons, suggesting that the measure assesses a quality of familism that persists across country of origin and language preference. Further, the results also support equality in mean factor levels across these groups.