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ERIC Number: EJ950985
Record Type: Journal
Publication Date: 2011-Dec
Pages: 5
Abstractor: As Provided
ISSN: ISSN-1072-0502
Decoding Overlapping Memories in the Medial Temporal Lobes Using High-Resolution fMRI
Chadwick, Martin J.; Hassabis, Demis; Maguire, Eleanor A.
Learning & Memory, v18 n12 p742-746 Dec 2011
The hippocampus is proposed to process overlapping episodes as discrete memory traces, although direct evidence for this in human episodic memory is scarce. Using green-screen technology we created four highly overlapping movies of everyday events. Participants were scanned using high-resolution fMRI while recalling the movies. Multivariate pattern analysis revealed that the hippocampus supported distinct representations of each memory, while neighboring regions did not, demonstrating that the human hippocampus maintains unique pattern-separated memory traces even when memories are highly overlapping. The hippocampus also contained representations of spatial contexts that were shared across different memories, consistent with a specialized role in processing space.
Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A