The aim of this study is to examine meaning in life, satisfaction with life, self-concept and locus of control among teachers by several variables. The research group was composed of 363 teachers (114 [40%] women, 219 [60%] men) working in several districts of Istanbul. The data were collected with Meaning in Life Scale (MLS), Satisfaction with Life Scale (SWLS), Social Comparison Scale (SCS), and Rotter's Locus of Control Scale (RLCS). Pearson's Correlation Analysis, Independent Samples T-Test and Mann Whitney-U and Kruskal-Wallis H test were utilized. A positive relationship was found between experienced meaning in life and satisfaction with life and self-concept while a negative relationship was found between experienced meaning in life and locus of control. Expected meaning in life, satisfaction with life and locus of control were found to differ by gender. It was also determined that expected meaning in life and self-concept differed by marital status.