While our perceptual experience seems to unfold continuously over time, episodic memory preserves distinct events for storage and recollection. Previous work shows that stability in encoding context serves to temporally bind individual items into sequential composite events. This phenomenon has been almost exclusively studied using visual and…

Formation of long-term synaptic plasticity that underlies long-term memory requires new protein synthesis. Years of research has elucidated some of the transcriptional and translational mechanisms that contribute to the production of new proteins. Early research on transcription focused on the transcription factor cAMP-responsive element binding…

The Remote Associates Test (RAT) is a word association retrieval task that consists of a series of problems, each with three seemingly unrelated prompt words. The subject is asked to produce a single word that is related to all three prompt words. In this paper, we provide support for a theory in which the RAT assesses a person's ability to…

Trauma's ubiquity in society leads to an acknowledgement that damaging experiences likely affect more students than they leave untouched. Dewey acknowledged the importance of the past throughout his theorizing of experience and simultaneously recognized that students need to draw upon past experiences in new learning encounters. In this paper, we…

The medial prefrontal cortex (mPFC) is known to be critical for specific forms of long-term recognition memory, however the cellular mechanisms in the mPFC that underpin memory maintenance have not been well characterized. This study examined the importance of phosphorylation of cAMP responsive element binding protein (CREB) in the mPFC for…

Differences in the learning associated transcriptional profiles between mouse strains with distinct learning abilities could provide insight into the molecular basis of learning and memory. The inbred mouse strain DBA/2 shows deficits in hippocampus-dependent memory, yet the transcriptional responses to learning and the underlying mechanisms of…

Cognitive control describes the ability to use internal goals to strategically guide how we process and respond to our environment. Changes in the environment lead to adaptation in control strategies. This type of control learning can be observed in performance adjustments in response to varying proportions of easy to hard trials over blocks of…

The open online course (MOOC) platform has seen an increase in usage, and there are a growing number of courses accessible for people to select. An effective method is urgently needed to recommend personalized courses for users. Although the existing course recommendation models consider that users' interests change over time, they often model…

This study investigated to what extent people can develop global spatial representations of a multiroom environment through one-shot physical walking between rooms. In Experiment 1, the participants learned objects' locations in one room of an immersive virtual environment. They were blindfolded and led to walk to a testing position either within…

The ubiquitin proteasome system (UPS) is a primary mechanism through which proteins are degraded in cells. UPS activity in the dorsal hippocampus (DH) is necessary for multiple types of memory, including object memory, in male rodents. However, sex differences in DH UPS activation after fear conditioning suggest that other forms of learning may…

This dissertation describes a program of research encompassing three studies that focused on examining the effects of enhanced expectancies and perceptions of success on motor learning. OPTIMAL theory (Wulf & Lewthwaite, 2016) proposes that practice manipulations that enhance a learner's expectations for future successful outcomes lead to…

Multiple epigenetic mechanisms, including histone acetylation and nucleosome remodeling, are known to be involved in long-term memory formation. Enhancing histone acetylation by deleting histone deacetylases, like HDAC3, typically enhances long-term memory formation. In contrast, disrupting nucleosome remodeling by blocking the neuron-specific…

Singular "they" is becoming increasingly common and accepted, but many people find it difficult to learn, instead making seemingly-counterintuitive errors like "she uses they/them pronouns." Existing pronoun production models argue that speakers select pronouns based on morphosyntactic information associated with a name, or…

Sensory integration takes place in the central nervous system where complex interactions such as co-ordination, attention, arousal levels, autonomic functioning, emotions, memory and higher level cognitive functions are carried out. Sensory integration gets information through the senses, puts it together with prior knowledge, information and…

Bilinguals employ both global and local control mechanisms to manage coactivated languages that compete for selection, yet little is known about how they operate on morphosyntactic information. The current study investigated bilingual language control mechanisms for a morphosyntactic production task. Across two experiments, 48 early…