This document is designed to provide practical information for teaching the Chemistry 20-30 Program of Studies. The first section provides an overview of Chemistry 20, explaining the program philosophy and the relationships among science, technology, and society. The use of concept connections and teaching a course around major science themes is described, as well as how the program articulates with the junior and senior high science courses. Section two contains four units. In unit one, students investigate a variety of solutions, learn of the characteristics of acids and bases, how to express concentration, and methods of preparing and handling solutions. In unit two, students are required to use mathematical manipulation and stoichiometric principles to predict quantities of substances consumed or produced in chemical reactions. In unit three, students are helped to relate theories about bonding to the properties of compounds and to develop explanations and descriptions of structure and bonding through scientific models. In unit four, students are introduced to the characteristics of organic compounds, the general nomenclature and formulas for hydrocarbon categories, their reactions and significant derivatives. The final section provides detailed information on a great variety of resources that support the implementation of this program. (ZWH)